Zero-mode waveguide metal nanoapertures are receiving a large interest owing to their ability to confine light at the nanoscale and enhance the fluorescence emission from single molecules. However, the interest for more advanced geometries beyond the vanilla circular shape remains badly understood. In a recent publication in Nanoscale Advances, int

The natural autofluorescence of proteins in the UV is appealing to get the detailed information from single molecule data without requiring a potentially disturbing external fluorescent label. However, proteins feature significantly lower autofluorescence brightness and photostabilities than conventional fluorescent dyes. This issue has largely pre

Since October, we welcome Prithu Roy as new PhD applicant in our group. Looking forward to exploring the nanoworld in UV!

Still not as famous on youtube as our esteemed colleague from Marseille, but going on the dark path

Förster resonance energy transfer (FRET) is widely used as a molecular ruler to monitor biomolecular conformations and interactions dynamics, but FRET is generally limited to distances below 10 nm. Last year, we showed that zero-mode waveguides (ZMW) nanoapertures can enable single molecule FRET detection at spatial distances exceeding 10 nm with

Soon our flag will flutter again over the Sea of Nanos. Wed. May 13th 2pm CEST: Ebbesen's Blade is on fly again. Thu. May 14th 3pm CEST: Shadow Princess took off and is fully operational. Fri. May 15th 12am CEST: Arcadia hashin! Thu. May 28th 4pm CEST: Queen Emeraldas Revenge is on fly. All our microscope setups are back and operational. Link to so

Resonant nanophotonics + gap antenna + microwave electromagnetism + filmed by my daughter + captain Harlock soundtrack + in my kitchen = blows my mind

Förster Resonance Energy Transfer (FRET) governs energy exchanges at the nanoscale and can be used to accurately measure intra- and inter-molecular distances with sub-nm accuracy. While photonic nanoantennas have been shown to modify FRET, most of the earlier experiments lacked the ability to manipulate the distance between the antenna and the emi

Zero-mode waveguide nanoapertures receive a large interest owing to their ability to confine light at the nanoscale and improve the detection of single fluorescent molecules. However, unwanted adhesion of the targeted molecules onto the metal surface can be a major issue. In a recent article published in Scientific Reports, we highlight the role of