We are opening a position for postdoctoral fellowship: experimental nanophotonics and plasmonic nano-optical tweezers. Read the details and apply through the CNRS institutional website: https://bit.ly/3HiobDC Position filled and no longer available. Contact Jerome Wenger for enquiries.

G-quadruplex structures of DNA are promising target sites for anticancer therapy. However, the interaction of G-quadruplex with proteins remains poorly understood, notably the association and dissociation kinetics. In a recent Nucleic Acid Research publication entitled “Fast interaction dynamics of G-quadruplex and RGG-rich peptides unveiled in z

We currently have two open positions with funding from China Scholarship Council CSC and Groupe Ecoles Centrales GEC-CSC: - One for a PhD: "UV autofluorescence microscopy" - One for a postdoc: "Fiber-integrated plasmonic nanotweezers to manipulate single proteins" Find them on the https://gec-csc.fr/ website with application form, section Natural &

Jerome will give an invited talk at the Biophysical Society Meeting next week. For those unable to join or for those just curious about it, here is a copy of the presentation slides about using metal nanoapertures to improve single molecule fluorescence detection. - BPSmeeting_Wenger_Feb22_export.pdf

Important Dates: • R egu lar submission deadline: September 6 , 20 2 2 • Reg ular registration deadline: October 4 , 20 2 2 • Conference: Oc t 25 - 2 7 , 20 2 2

We are thrilled to announce the arrival of our newest PhD student, Malavika Kayyil Veedu, who will be joining us for the next three years. She will be working with us on a cutting-edge research project on plasmonics-enhanced fluorescence and nanopores. Malavika comes to us as part of the Marie Curie research program doctoral network called Dynamo,

Proteins are naturally fluorescent in the ultraviolet, offering an appealing approach to probe proteins in their native state without introducing any external fluorescent label. The UV autofluorescence of proteins is based on the presence of tryptophan amino acids, which typically occur as 1 to 5 tryptophan per protein. However, due to weak signals

One of the ultimate goals of molecular biology is to watch how single proteins work in their native state. The current mainstream approach of single molecule fluorescence relies on introducing external fluorescent markers which can lead to severe issues affecting the experimental results. As an alternative to fluorescence labelling, working in the

Within the Marie Skłodowska-Curie Doctoral Networks DYNAMO merging of 6 world-leading academic groups and 1 high tech company, we are offering one full PhD fellowship on plasmonic trapping and enhanced UV label-free single protein detection with plasmonic nanopores. See the complete details in the description enclosed below. The application websit

Proteins can feature ultrafast structural dynamics in the nanosecond timescale which are very challenging to measure using conventional techniques such as single-molecule Förster resonance energy transfer (smFRET). So far, the limited fluorescence brightness and the relatively long fluorescence lifetimes have limited the temporal resolution of smF